Hey Mids. Searched boards for "lysosome" and "lyso" with no results, so:
Lysosomes Exposure Hami-Os are incorrectly improving just ToHit Buffs, instead of ToHit Debuffs. Yes, I know that there's the whole *hushed whisper* exploit! with using Lysosomes and Membranes interchangeably in powers that accept either Accuracy or Recharge slots, but Lysosomes are showing ToHit, and ONLY ToHit, instead of ToHit Debuff.
...tl;dr: Lyso needs the + sign on +tohit swapped to a -.