As someone who was diagnosed with Aspergers Syndrome(a.k.a., High Functioning Autism) in 2000(despite being 28 at the time), and who, in part because of this, is prone to wild mood swings of which I have little to no control over('Aspies' have 2 emotional settings: off and FULL BLAST), I can offer -some- advice....
Paxil had some effect on me, but wasn't enough...we then tried Buspar(spelling?), which also had little effect...; a 3rd attempt combined the 2...and it worked...-too- well...my emotions all but totally shut down...we dropped this combination shortly thereafter, and, with a little help from friends and family, and a VERY knowledgeable doctor(who is the editor-in-chief of Exceptional Parent magazine), I've made big steps in dealing with things!
It's by no means beaten, but I've learned how to suppress a lot of the problems, or at least offset them....
...and yes, City of Heroes has done an IMMENSE amount of good for me, enabling me to do one of the things I do best...tell a story...I got to bring an original character I'd been writing about for 7 years, as of 2004, to 'life'...the AE system had, of course, been a god-send....
So, of course it hit me like a hammer that fateful day when I saw the news...I'd been hoping I could make a comeback, but real-life kept getting in the way('stupid real-life...you go SQUISH, now!')....
But rest assured...even if I can't get back in-game...I'll find a way to support the cause....