the interest amongst casual gamers and even non-gamers in superheroes is at an all time high, the superhero industry in film and in video games is making more money than ever before, as evidenced by the tremendous sales of the marvel cinematic universe films, especially the avengers, and the massive interest and hype over the release of injustice 2. If there was ever a time to release a superhero game, even reviving an old one, it would be right now
31 superhero films were released during the lifespan of CoX there is *NO* guarantee that being a "Comic Book film" would be a sign of success. Hell, even in the *TV* world, there is no guarantee that being based on a superhero property will mean you will keep on running[2]
Also, it is worth noting that *considering* the wide range of films and amount that are getting released.... I would say that the most successful game franchise isn't even made from comics... but Lego Bricks. The Batman Arkham series is good as well. Apart from those 2 franchises, well... the games have been hit and miss in terms of quality over the years.
[1] 20 films based on Marvel properties, 11 films based on DC properties. And this is just the *live action* stuff. Animated/TV properties bring this total up even higher. And I am also not counting films like RED, Men In Black, Kick Ass which were comics before films.
[2] Agent Carter, Constantine for example.